标签归档:SV

2016
12-21
Identification of complex genomic rearrangements in cancers using CouGaR Abstract The genomic alterations associated with cancers are numerous and.... Read More >
2016
12-14
Discovery and genotyping of structural variation from long-read haploid genome sequence data Abstract In an effort to more fully understand the full spectrum of human genetic variation, we generat.... Read More >
2016
12-14
novoBreak: local assembly for breakpoint detection in cancer genomes Abstract We present novoBreak, a genome-wide local assembly algorithm that di.... Read More >
2016
03-20
Mechanisms underlying structural variant formation in genomic disorders. Abstract With the recent burst of technological developments in genomics, and the clinical implementation of genome-wide as.... Read More >
2016
02-18
SV-融合基因的可视化展示形式-1 http://bioinfo.ibp.ac.cn/biocircos/gallery11.php SV-融合基因的可视化展示形式-2,适合crest及lumpy软件基于soft-clip reads http://www.10xgenomics.co.... Read More >
2015
12-23
Comprehensive characterization of complex structural variations in cancer by directly comparing genome sequence reads Abstract The development of hi.... Read More >
2015
12-23
LUMPY: a probabilistic framework for structural variant discovery Abstract Comprehensive discovery of structural variation (SV) from whole genom.... Read More >
2015
12-21
前言:目前利用全基因组测序方法研究肿瘤的越来越普遍,在实际的应用过程中,有一点一直困惑笔者:如何检测高频somatic SV,这里的SV包括插入,缺失CNV,还包括倒位,易位等拷贝数中性SV。需要区分的是目前做高频CNV的方法比较成熟,可以直接使用GISTIC软件。直接以SV涉及的基因进行统计的文献.... Read More >
2015
12-21
Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Abstract Neuroblastoma is a malignant paediatric tumour of the sym.... Read More >