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2015
12-30
EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors. Abstract The EML4 (echinoderm microtubule-associated protein-like 4)-ALK (anaplastic lymphoma kinase) fusion-type ty.... Read More >
2015
12-30
Whole-Exome Sequencing in Familial Parkinson Disease. Abstract IMPORTANCE: Parkinson disease (PD) is a progressive neurodegenerative disease for .... Read More >
2015
12-30
Cancer Genomics: Diversity and Disparity Across Ethnicity and Geography. Abstract Ethnic and geographic differences in cancer incidence, prognosis.... Read More >
2015
12-30
The contribution of rare variation to prostate cancer heritability Abstract We report targeted sequencing of 63 known prostate cancer risk regions in a multi-ancestry study of 9,237 men and use th.... Read More >
2015
12-30
Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution. Abstract The prevailing view that the.... Read More >
2015
12-30
Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. Abstract IMPORTANCE: Tumor genetic sequencing identifies potentially targetable genetic alterations with therapeutic impli.... Read More >
2015
12-30
The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome Abstract Sézary syndrome is a leukemic and aggressive form of cutaneous T cell lymphoma (CTCL) resulting from the malignan.... Read More >
2015
12-29
The Molecular Taxonomy of Primary Prostate Cancer Abstract There is substantial heterogeneity among primary prostate cancers, evident in the spe.... Read More >
2015
12-29
Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease. Abstract Development of the human nervous system involves complex interactions amo.... Read More >
2015
12-27
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. Abstract Background Papillary renal-cell carcinoma, which accounts for.... Read More >