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2016
01-21
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity Abstract Intratumor heterogeneity (ITH) drives neoplastic progression and therapeutic resistance. We used the bioinfo.... Read More >
2016
01-21
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity Abstract Mutational hotspots indicate selective pressure across a population of tumor sample.... Read More >
2016
01-21
Germline Mutations in Predisposition Genes in Pediatric Cancer. Abstract Background The prevalence and spectrum of predisposing mutations among children and adolescents with cancer are largely unk.... Read More >
2016
01-19
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects Abstract CRISPR–Cas9 nucleases are widely used for genome edit.... Read More >
2016
01-19
Deep learning Abstract Deep learning allows computational models that are composed of multiple processing layers to learn representations of data with multiple levels of abstraction. These methods h.... Read More >
2016
01-19
Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning Abstract Knowing the sequence specificities of DNA- and RNA-.... Read More >
2016
01-19
Predicting effects of noncoding variants with deep learning–based sequence model Abstact Identifying functional effects of noncoding variants is a major challenge in human genetics. To predict the.... Read More >
2016
01-15
非常棒的谷歌镜像网址,该网址可以自动寻找可用的谷歌镜像,图片及学术均可用,也可以在右上角自己调整镜像地址。 谷歌学术地址:http://guge.suanfazu.com/?c=scholar.... Read More >
2015
12-30
http://www.deepgenomics.com/,很有趣的公司。后面基因组大数据的挖掘,deep learning必然是被热炒的概念。 http://blog.csdn.net/abcjennifer/article/details/7826917,一个deep learing.... Read More >
2015
12-30
Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency. Abstract Osteosarcomas are aggressive bone tumours with a high degree of genetic heterogeneity, which h.... Read More >