分类目录归档:GWAS

2016
12-14
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals Abstract To dissect the genetic architecture of blood pressure and assess effects on.... Read More >
2016
12-14
Genome-wide analysis identifies 12 loci influencing human reproductive behavior Abstract The genetic architecture of human reproductive behavior—age at first birth (AFB) and number of children eve.... Read More >
2016
03-20
Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. BACKGROUND & AIMS: Known Genetic factors explain only a small fraction of genetic variation in colorectal cancer (CR.... Read More >
2015
12-30
The contribution of rare variation to prostate cancer heritability Abstract We report targeted sequencing of 63 known prostate cancer risk regions in a multi-ancestry study of 9,237 men and use th.... Read More >
2015
12-16
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Abstract The extent to which low-frequency (minor allele frequency (MAF) between 1-5%) and rare (MAF ≤ 1%) var.... Read More >
2015
12-16
The UK10K project identifies rare variants in health and disease. Abstract The contribution of rare and low-frequency variants to human traits is .... Read More >
2015
07-06
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer   Pancreatic cancer is the fourth lead.... Read More >
2015
07-06
BACKGROUND: ABCA7 was identified as a risk gene for Alzheimer's disease in genome-wide association studies (GWAS). It was one of the genes most strongly associated with risk of Alzheimer's disease in.... Read More >
2015
07-03
Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies Abstract Recent advances in genome-wide association studies (GWAS) across autoimmune .... Read More >
2015
04-14
Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening Abstract Idiopathic pulmonary fi.... Read More >